Acrocephalosyndactyly Syndrome: Challenging Diagnosis

Postsurgical Parsonage-Turner syndrome: a challenging diagnosis.

Parsonage-Turner syndrome (PTS) is a distinct clinical syndrome, characterized by acute and severe (mostly) unilateral shoulder pain, followed by paresis and atrophy of the shoulder girdle, while the pain decreases. Most authors consider it as an immune-mediated disorder. PTS is notoriously unrecognised and is usually diagnosed with delay. A PTS may also occur following a surgical procedure. Po...

polycystic ovary syndrome: an apparently simple yet challenging diagnosis

Sweet's syndrome associated with cellulitis - a challenging diagnosis*

Sweet's syndrome is a neutrophilic dermatosis with worldwide distribution that has been associated with inflammatory autoimmune diseases, infections, malignancies, drugs, and pregnancy. The disease is idiopathic in up to 50% of patients. A 64-year-old woman, diagnosed with right limb cellulitis (4 days of evolution), was seen at our department, due to persistent cellulitis and progressive appea...

Late Differentiation Syndrome in Acute Promyelocytic Leukemia: A Challenging Diagnosis

Detailed knowledge about differentiation syndrome (DS) has remained limited. There are 2 large studies conducted by the Spanish workgroup PETHEMA (Programa Español de Tratamientos en Hematología; Spanish Program on Hematology Treatments) and the European group trial (LPA 96-99 and APL 93) in which the incidence, characteristics, prognostic factors and outcome of patients developing DS are evalu...

Polycystic Ovary Syndrome: An Apparently Simple yet Challenging Diagnosis

Polycystic Ovary Syndrome (PCOS), also known as Stein-Leventhal syndrome, had first been described in 1935 as amenorrhea associated with bilateral polycystic ovaries (PCO). Since that moment, its definition has been changed several times. In 1990, according to the National Institutes of Health criteria, PCOS was diagnosed when both ovulatory dysfunction and clinical hyperandrogen-ism and/or hyp...